LIVE POLL: What Makes Orange Cats So Darn Animated?

The Baron

Tabby apparently refers to a pattern, and the cats from Aristocats don't have any pattern. Perhaps you could just say "orange cats"?

While he is not a cat, if Hobbes can be included in option 8 as the title Dear Mr. Watterson suggest, then I'll go with him.

@Tsarstepan, @Jessica, @Peter_pbn and @Pencho15, There are recent published reports about Orange cats. Orange cats are genetically special due to a unique mutation on their X chromosome that controls their orange fur color. Here's what makes them stand out: Sex-linked gene: The gene responsible for orange fur (often called the "orange" or "O" gene) is located on the X chromosome. This is crucial because male cats have one X and one Y chromosome (XY), while female cats have two X chromosomes (XX). Male predominance: Because males only need one copy of the orange gene on their single X chromosome to be orange, approximately 80% of orange cats are male. If a male cat inherits the orange gene, he will be entirely orange. Female genetics: For a female cat to be entirely orange, she must inherit the orange gene on both of her X chromosomes. This is less likely to happen, especially since the frequency of the orange gene can be lower than other color genes in the cat population. Tortoiseshell and Calico patterns: Female cats who inherit one orange gene and one non-orange gene on their two X chromosomes will display a mottled pattern of orange and black (or other colors) known as tortoiseshell or calico. This is due to a phenomenon called random X-inactivation, where one X chromosome is randomly inactivated in each cell during development, leading to patches of different colors. This is why nearly all tortoiseshell and calico cats are female. The ARHGAP36 gene: Recent research has identified a specific deletion in the X-linked gene called ARHGAP36 as the cause of orange coloration. This deletion leads to increased activity of the ARHGAP36 gene in pigment cells, which then shifts pigment production from dark eumelanin to lighter pheomelanin (the pigment that creates orange fur). This mutation appears to be unique to domestic cats among mammals. Tabby patterns: All orange cats are genetically tabbies. Even if they appear "solid" orange, they are technically low-contrast ticked tabbies. This is because the orange gene is epistatic (meaning it overrides) to the non-agouti gene, which would otherwise result in a solid color. In essence, the unique way the orange gene is inherited on the X chromosome explains the high proportion of male orange cats and the distinctive appearance of tortoiseshell and calico females.

Live Poll: https://www.imdb.com/poll/wyGnTOnOO20/ Congratulations TsarStepan